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There are several matches for 'probable nuclease'.
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151 matches
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organism
protein
1)
Homo sapiens
MCM9 - DNA helicase MCM9; Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross- links (ICLs) by homologous recombination (HR). Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex
nuclease
activity.
Probably
by regulating the localization of the MRN complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs. Acts as a helicase in DNA mismatch repair (MMR) followin [...]
[a.k.a. B9DI77, UPI0001D3BCDF, MGC35304]
2)
Homo sapiens
MCM8 - DNA helicase MCM8; Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross- links (ICLs) by homologous recombination (HR). Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex
nuclease
activity.
Probably
by regulating the localization of the MNR complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs. The MCM8-MCM9 complex is dispensable for DNA replication [...]
[a.k.a. XM_011529387, R-HSA-69278, R-HSA-69620]
3)
Homo sapiens
FAN1 - Fanconi-associated
nuclease
1;
Nuclease
required for the repair of DNA interstrand cross- links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination,
probably
in the resolution of homologous recombination intermediates. Not involved in DNA double-strand breaks resection. Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Pro [...]
[a.k.a. FAN1-207, ENST00000565280, ENST00000664837]
4)
Mus musculus
Mcm8 - DNA helicase MCM8; Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross- links (ICLs) by homologous recombination (HR). Required for DNA resection by the MRE11-RAD50-NBN/NBS1 (MRN) complex by recruiting the MRN complex to the repair site and by promoting the complex
nuclease
activity.
Probably
by regulating the localization of the MNR complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs and ICLs. The MCM8-MCM9 complex is dispensable for DNA replication [...]
[a.k.a. Mcm8-202, R-MMU-453279, R-MMU-69306]
5)
Mus musculus
Mcm9 - DNA helicase MCM9; Component of the MCM8-MCM9 complex, a complex involved in the repair of double-stranded DNA breaks (DBSs) and DNA interstrand cross- links (ICLs) by homologous recombination (HR). Required for DNA resection by the MRE11-RAD50- NBN/NBS1 (MRN) complex at double-stranded DNA breaks to generate ssDNA by recruiting the MRN complex to the repair site and by promoting the complex
nuclease
activity (By similarity).
Probably
by regulating the localization of the MNR complex, indirectly regulates the recruitment of downstream effector RAD51 to DNA damage sites including DBSs a [...]
[a.k.a. ENSMUSP00000074978, Mcm9-205, 9030408O17Rik]
6)
Mus musculus
Fan1 - Fanconi-associated
nuclease
1;
Nuclease
required for the repair of DNA interstrand cross- links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination,
probably
in the resolution of homologous recombination intermediates (By similarity). Not involved in DNA double-strand breaks resection. Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flankin [...]
[a.k.a. ENSMUSP00000130012, uc012fmp.1, FANCD2/FANCI-associated nuclease 1]
7)
Drosophila melanogaster
Tudor-SN - Staphylococcal
nuclease
domain-containing protein 1; Endonuclease which shows activity towards both DNA and RNA substrates. Has a role in translation regulation throught its association with the with the RNA- induced silencing complex (RISC). Plays a role in spermatogenesis
probably
by negatively regulating piwi expression in the germline. Together with piwi, might be involved in transposon repression in the germline.
[a.k.a. FBgn0035121, Tudor-SN-PB, Tudor-SN-PA]
8)
Escherichia coli K12
csrD - Targeting factor for csrBC sRNA degradation; Serves as a specificity factor required for RNase E-mediated decay of the small global regulatory RNAs CsrB and CsrC, it is
probably
not a
nuclease
. Nor does its activity involve c-di-GMP, despite its domain composition. Positively modulates motility gene expression, is also required for curli expression.
[a.k.a. b3252, AAC76284.1, Q2M8W2]
9)
Saccharomyces cerevisiae
LCL3 -
Probable
endonuclease LCL3; Putative protein of unknown function; mutant has long chronological lifespan; has homology to Staphylococcus aureus
nuclease
; GFP-fusion protein localizes to mitochondria; is induced in response to the DNA-damaging agent MMS.
[a.k.a. YGL085W, NP_011430, D6VU59]
10)
Escherichia coli K12
yadD - Transposase_31 family protein; A low activity DNA endonuclease yielding 3'-hydroxyl ends (
Probable
). Upon expression enhances RecA-independent DNA recombination 2.9-fold, concomitantly reducing viability by 59% and inducing DNA damage as measured by induction of the SOS repair response. Belongs to the Rpn/YhgA-like
nuclease
family.
[a.k.a. AAC73243.1, b0132, P75660]
11)
Escherichia coli K12
yfcI - Transposase_31 family protein; A low activity DNA endonuclease yielding 3'-hydroxyl ends (
Probable
). Upon expression enhances RecA-independent DNA recombination 19-fold, concomitantly reducing viability by 98% and inducing DNA damage as measured by induction of the SOS repair response. Belongs to the Rpn/YhgA-like
nuclease
family.
[a.k.a. b2305, AAC75365.1, EG14112]
12)
Escherichia coli K12
uvrB - Exision
nuclease
of nucleotide excision repair, DNA damage recognition component; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and
probably
causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesi [...]
[a.k.a. b0779, AAC73866.1, P0A8F8]
13)
Brevibacillus brevis
BAH42925.1 -
Probable
nuclease
.
[a.k.a. BBR47_19480, C0ZAW6_BREBN, 29259257,
probable nuclease
,
Probable nuclease
, ...]
14)
Mariprofundus ferrooxydans
KON48289.1 - Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
[a.k.a. AL013_02845, nuclease, Q0EXB8_9PROT,
Probable nuclease
]
15)
Pseudomonas aeruginosa
PA3232 -
Probable
nuclease
; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
[a.k.a. AAG06620.1, NP_251922.1, NC_002516.2,
probable nuclease
,
Probable nuclease
, ...]
16)
Pseudomonas aeruginosa
PA4172 -
Probable
nuclease
; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
[a.k.a. AAG07559.1, Exodeoxyribonuclease III, AAG07559,
probable nuclease
,
Probable nuclease
, ...]
17)
Pseudomonas aeruginosa
PA5048 -
Probable
nuclease
; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
[a.k.a. AAG08433.1, pae:PA5048, NP_253735.1,
probable nuclease
,
Probable nuclease
, ...]
18)
gamma proteobacterium HdN1
CBL45911.1 -
Probable
nuclease
; silverDB:HdN1F3097.
[a.k.a. HDN1F_23280, E1VM69_9GAMM, IPR016071,
Probable nuclease
]
19)
Fluviicola taffensis
AEA45328.1 - Polymorphic outer membrane protein; InterPro IPR006626:IPR003368; KEGG: cat:CA2559_10338
probable
extracellular
nuclease
; PFAM: Polymorphic membrane protein, Chlamydia; SPTR:
Probable
extracellular
nuclease
; TIGRFAM: Polymorphic membrane protein, Chlamydia.
[a.k.a. Fluta_3356, Polymorphic outer membrane protein, AEA45328]
20)
Campylobacter jejuni NCTC 11168
Cj0979c - Putative secreted
nuclease
; Original (2000) note: Cj0979c,
probable
secreted
nuclease
, len: 175 aa; similar to many e.g. NUC_STAHY thermonuclease precursor (EC 3.1.31.1) (169 aa), fasta scores; opt: 206 z-score: 261.7 E(): 2.8e-07, 36.9% identity in 122 aa overlap. No Hp match. Contains possible N-terminal signal sequence and Pfam match to entry PF00565 SNase, Staphylococcal
nuclease
homologues; Updated (2006) note: Some characterisation work in Staphylococcus spp. Putative kept in product function. Functional classification - Degradation of macromolecules - DNA; PMID:67041918.
[a.k.a. CAL35097.1, YP_002344374.1, 905270]
151 matches
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